No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
3532 |
4. Check minimum number of eventsNone |
3532 |
5. Include endpointsNone |
3532 |
6. Filter based on genotype QC (FinnGen only) |
3378 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
First used in FinnGen datafreeze
DF10
Similar endpoints
↥List of similar endpoints to
Embedded teeth, including avohilmo
based on the number of shared cases.
Similar with more cases:
- Tooth eruption problems
- Embedded and impacted teeth
- Diseases of oral cavity, salivary glands and jaws
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 41806 | 23958 | 17720 |
| Only index persons | 40280 | 23276 | 17004 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.60 | 0.69 | 0.50 |
| Only index persons | 0.77 | 0.86 | 0.65 |
| Median age at first event (years) | |||
| Whole population | 23.49 | 23.48 | 23.45 |
| Only index persons | 23.68 | 23.67 | 23.68 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3378 | 2333 | 1045 |
| Unadjusted period prevalence (%) | 0.80 | 0.92 | 0.52 |
| Median age at first event (years) | 28.09 | 26.76 | 31.05 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint K11_EMBED_TEETH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_EMBED_TEETH | 1.341 [1.11, 1.62] | 0.003 |
| Birth year | 0.999 [0.99, 1.01] | 0.849 |
During the follow-up period (1.1.1998 — 31.12.2019), 390 out of 20148 females with K11_EMBED_TEETH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_EMBED_TEETH | 1.447 [1.23, 1.7] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.016 |
During the follow-up period (1.1.1998 — 31.12.2019), 679 out of 14936 males with K11_EMBED_TEETH died.
Mortality risk
Mortality risk for people of age
years, who have K11_EMBED_TEETH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.129% | 0.248% |
| 5 | 0.76% | 1.574% |
| 10 | 2.17% | 4.223% |
| 15 | 4.374% | 8.045% |
| 20 | 7.752% | 13.53% |
Relationships between endpoints
↥Index endpoint: K11_EMBED_TEETH – Embedded teeth, including avohilmo
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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