esophageal disease: A non-neoplastic or neoplastic disorder that affects the esophagus. Representative examples of non-neoplastic disorders include esophagitis and esophageal ulcer. Representative examples of neoplastic disorders include carcinomas, lymphomas, and melanomas.
Disorders of oesophagus in diseases classified elsewhere
DOID EFO Endpoint Browser PheWeb
K11_DISOESINOTH
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
643 |
4. Check minimum number of eventsNone |
643 |
5. Include endpointsNone |
643 |
6. Filter based on genotype QC (FinnGen only) |
620 |
Control definitions (FinnGen only)
Extra metadata
Similar endpoints
↥List of similar endpoints to Disorders of oesophagus in diseases classified elsewhere based on the number of shared cases.
Similar with more cases:
- Diseases of oesophagus, stomach and duodenum
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 4359 | 2111 | 2210 |
Only index persons | 3741 | 1874 | 1867 |
Unadjusted period prevalence (%) | |||
Whole population | 0.06 | 0.06 | 0.06 |
Only index persons | 0.07 | 0.07 | 0.07 |
Median age at first event (years) | |||
Whole population | 68.90 | 69.62 | 68.24 |
Only index persons | 68.35 | 68.82 | 67.87 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 620 | 304 | 316 |
Unadjusted period prevalence (%) | 0.14 | 0.12 | 0.16 |
Median age at first event (years) | 66.44 | 64.25 | 68.54 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint K11_DISOESINOTH and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
K11_DISOESINOTH | 2.565 [2.19, 3.01] | < 0.001 |
Birth year | 0.999 [0.99, 1.01] | 0.903 |
During the follow-up period (1.1.1998 — 31.12.2019), 765 out of 1795 females with K11_DISOESINOTH died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
K11_DISOESINOTH | 3.311 [2.69, 4.07] | < 0.001 |
Birth year | 0.985 [0.97, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 950 out of 1818 males with K11_DISOESINOTH died.
Mortality risk
Mortality risk for people of age
years, who have K11_DISOESINOTH.N-year risk | Females | Males |
---|---|---|
1 | 0.301% | 0.578% |
5 | 1.533% | 3.549% |
10 | 4.232% | 8.764% |
15 | 8.451% | 15.944% |
20 | 14.532% | 26.073% |
Relationships between endpoints
↥Index endpoint: K11_DISOESINOTH – Disorders of oesophagus in diseases classified elsewhere
GWS hits: 1