No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2586 |
4. Check minimum number of eventsNone |
2586 |
5. Include endpointsNone |
2586 |
6. Filter based on genotype QC (FinnGen only) |
2432 |
Control definitions (FinnGen only)
Control exclude
K11_ORAL
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF5
Similar endpoints
↥List of similar endpoints to
Deposits [accretions] on teeth
based on the number of shared cases.
Similar with more cases:
- Other diseases of hard tissues of teeth
- Diseases of oral cavity, salivary glands and jaws
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 18800 | 8339 | 10379 |
| Only index persons | 15591 | 7013 | 8578 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.27 | 0.24 | 0.29 |
| Only index persons | 0.30 | 0.26 | 0.33 |
| Median age at first event (years) | |||
| Whole population | 33.24 | 33.99 | 32.58 |
| Only index persons | 41.43 | 42.14 | 40.86 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2432 | 1155 | 1277 |
| Unadjusted period prevalence (%) | 0.55 | 0.45 | 0.64 |
| Median age at first event (years) | 53.50 | 51.84 | 55.00 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint K11_DEPOSITS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_DEPOSITS | 4.521 [3.73, 5.48] | < 0.001 |
| Birth year | 0.999 [0.99, 1.01] | 0.736 |
During the follow-up period (1.1.1998 — 31.12.2019), 851 out of 6303 females with K11_DEPOSITS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_DEPOSITS | 4.262 [3.54, 5.13] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.021 |
During the follow-up period (1.1.1998 — 31.12.2019), 1342 out of 7931 males with K11_DEPOSITS died.
Mortality risk
Mortality risk for people of age
years, who have K11_DEPOSITS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.493% | 0.703% |
| 5 | 2.553% | 5.091% |
| 10 | 7.352% | 12.193% |
| 15 | 13.78% | 22.345% |
| 20 | 22.891% | 35.248% |
Relationships between endpoints
↥Index endpoint: K11_DEPOSITS – Deposits [accretions] on teeth
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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