chronic gastritis: Inflammation of the stomach that is chronic in nature.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2893 |
4. Check minimum number of eventsNone |
2893 |
5. Include endpointsNone |
2893 |
6. Filter based on genotype QC (FinnGen only) |
2770 |
Control definitions (FinnGen only)
Control exclude
K11_OESSTODUO
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Acute gastritis
based on the number of shared cases.
Similar with more cases:
- Diseases of oesophagus, stomach and duodenum
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 29046 | 14553 | 14180 |
| Only index persons | 22721 | 11717 | 11004 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.41 | 0.42 | 0.40 |
| Only index persons | 0.43 | 0.43 | 0.42 |
| Median age at first event (years) | |||
| Whole population | 59.00 | 62.12 | 55.63 |
| Only index persons | 55.57 | 58.04 | 52.93 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2770 | 1458 | 1312 |
| Unadjusted period prevalence (%) | 0.61 | 0.57 | 0.66 |
| Median age at first event (years) | 55.90 | 53.33 | 58.76 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint K11_ACUTGASTR and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_ACUTGASTR | 1.501 [1.39, 1.62] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.505 |
During the follow-up period (1.1.1998 — 31.12.2019), 3509 out of 10649 females with K11_ACUTGASTR died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_ACUTGASTR | 1.956 [1.79, 2.13] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 3690 out of 9494 males with K11_ACUTGASTR died.
Mortality risk
Mortality risk for people of age
years, who have K11_ACUTGASTR.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.169% | 0.302% |
| 5 | 0.945% | 2.288% |
| 10 | 2.344% | 5.938% |
| 15 | 4.395% | 10.628% |
| 20 | 7.829% | 17.594% |
Relationships between endpoints
↥Index endpoint: K11_ACUTGASTR – Acute gastritis
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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