≡ Risteys
FG R11 + FR

Documentation Changelog GitHub Contact & Feedback

Other pleural conditions

DOID EFO Endpoint Browser PheWeb

J10_PLEUROTH

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — J94
  • Hospital discharge: ICD-9 — 511
  • Hospital discharge: ICD-8 — 511
  • Hospital discharge: excluded ICD-9 — 5111
  • Hospital discharge: excluded ICD-8 — 511[1-2]
  • Cause of death: ICD-10 — J94
  • Cause of death: ICD-9 — 511
  • Cause of death: ICD-8 — 511
  • Cause of death: excluded ICD-9 — 5111
  • Cause of death: excluded ICD-8 — 511[1-2]

2 out of 7 registries used, show all original rules.

3666

4. Check minimum number of events

None

3666

5. Include endpoints

None

3666

6. Filter based on genotype QC (FinnGen only)

3545

Control definitions (FinnGen only)

Control exclude J10_PLEURA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 J90-J94
Name in latin Aliae morbositates pleurae

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 35764 13302 21866
Only index persons 25352 10084 15268
Unadjusted period prevalence (%)
Whole population 0.53 0.38 0.61
Only index persons 0.50 0.37 0.58
Median age at first event (years)
Whole population 67.99 70.47 66.53
Only index persons 68.38 70.79 66.78

-FinnGen-

Key figures

All Female Male
Number of individuals 3545 1173 2372
Unadjusted period prevalence (%) 0.95 0.46 1.19
Median age at first event (years) 66.79 66.04 67.17

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

↥

Association

Association between endpoint J10_PLEUROTH and mortality.

Females

Parameter HR [95% CI] p-value
J10_PLEUROTH 5.148 [4.33, 6.12] < 0.001
Birth year 0.989 [0.98, 1.0] 0.013

During the follow-up period (1.1.1998 — 31.12.2019), 4491 out of 7479 females with J10_PLEUROTH died.

Males

Parameter HR [95% CI] p-value
J10_PLEUROTH 3.722 [3.21, 4.31] < 0.001
Birth year 0.989 [0.98, 1.0] 0.017

During the follow-up period (1.1.1998 — 31.12.2019), 6334 out of 11188 males with J10_PLEUROTH died.

Mortality risk

Mortality risk for people of age

years, who have J10_PLEUROTH.

N-year risk Females Males
1 0.428% 0.56%
5 2.282% 4.013%
10 5.981% 9.919%
15 11.678% 18.879%
20 19.82% 31.195%

Relationships between endpoints

↥

Index endpoint: J10_PLEUROTH – Other pleural conditions

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data