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Peritonsillar abscess

DOID EFO Endpoint Browser PheWeb

J10_PERITONSABSC

peritonsillar abscess: An abscess that develops in the space surrounding one or both palatine tonsils.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — J36
  • Hospital discharge: ICD-9 — 475
  • Hospital discharge: ICD-8 — 501
  • Cause of death: ICD-10 — J36
  • Cause of death: ICD-9 — 475
  • Cause of death: ICD-8 — 501

2 out of 7 registries used, show all original rules.

9645

4. Check minimum number of events

None

9645

5. Include endpoints

None

9645

6. Filter based on genotype QC (FinnGen only)

9339

Control definitions (FinnGen only)

Control exclude J10_UPPERDIS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 J30-J39
Name in latin Abscessus peritonsillaris

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 105717 47161 58191
Only index persons 100359 45452 54907
Unadjusted period prevalence (%)
Whole population 1.50 1.35 1.63
Only index persons 1.90 1.67 2.10
Median age at first event (years)
Whole population 23.44 22.05 24.49
Only index persons 23.04 21.88 24.00

-FinnGen-

Key figures

All Female Male
Number of individuals 9339 5183 4156
Unadjusted period prevalence (%) 2.06 2.04 2.09
Median age at first event (years) 27.71 23.69 32.73

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Association

Association between endpoint J10_PERITONSABSC and mortality.

Females

Parameter HR [95% CI] p-value
J10_PERITONSABSC 1.022 [0.89, 1.18] 0.76
Birth year 0.992 [0.98, 1.0] 0.072

During the follow-up period (1.1.1998 — 31.12.2019), 881 out of 28013 females with J10_PERITONSABSC died.

Males

Parameter HR [95% CI] p-value
J10_PERITONSABSC 1.074 [0.96, 1.2] 0.213
Birth year 0.991 [0.98, 1.0] 0.05

During the follow-up period (1.1.1998 — 31.12.2019), 1802 out of 33169 males with J10_PERITONSABSC died.

Mortality risk

Mortality risk for people of age

years, who have J10_PERITONSABSC.

N-year risk Females Males
1 0.102% 0.28%
5 0.52% 1.402%
10 1.323% 3.387%
15 2.593% 6.6%
20 4.652% 11.055%

Relationships between endpoints

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Index endpoint: J10_PERITONSABSC – Peritonsillar abscess

GWS hits: 13

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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