bronchitis: An acute or chronic inflammatory process affecting the bronchi. [database_cross_reference: NCIT:C2911]
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1419 |
4. Check minimum number of eventsNone |
1419 |
5. Include endpointsNone |
1419 |
6. Filter based on genotype QC (FinnGen only) |
1373 |
Control definitions (FinnGen only)
Extra metadata
Similar endpoints
↥List of similar endpoints to Unspecified chronic bronchitis based on the number of shared cases.
Similar with more cases:
- Chronic lower respiratory diseases
- Excluding asthma or asthma-COPD overlap
- COPD differential diagnosis
- ILD differential diagnosis
- Diseases of the respiratory system
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 18442 | 6735 | 11129 |
Only index persons | 8641 | 4155 | 4486 |
Unadjusted period prevalence (%) | |||
Whole population | 0.28 | 0.19 | 0.31 |
Only index persons | 0.16 | 0.15 | 0.17 |
Median age at first event (years) | |||
Whole population | 61.97 | 59.69 | 63.16 |
Only index persons | 54.81 | 54.34 | 55.24 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 1373 | 484 | 889 |
Unadjusted period prevalence (%) | 0.36 | 0.19 | 0.45 |
Median age at first event (years) | 57.45 | 53.57 | 59.56 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint J10_BRONCHNAS and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
J10_BRONCHNAS | 1.856 [1.65, 2.08] | < 0.001 |
Birth year | 0.995 [0.99, 1.0] | 0.249 |
During the follow-up period (1.1.1998 — 31.12.2019), 1058 out of 2991 females with J10_BRONCHNAS died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
J10_BRONCHNAS | 2.101 [1.86, 2.37] | < 0.001 |
Birth year | 0.986 [0.98, 0.99] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 1766 out of 3561 males with J10_BRONCHNAS died.
Mortality risk
Mortality risk for people of age
years, who have J10_BRONCHNAS.N-year risk | Females | Males |
---|---|---|
1 | 0.175% | 0.429% |
5 | 0.997% | 2.609% |
10 | 2.501% | 6.064% |
15 | 5.092% | 10.933% |
20 | 8.903% | 18.446% |
Relationships between endpoints
↥Index endpoint: J10_BRONCHNAS – Unspecified chronic bronchitis
GWS hits: -