No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2686 |
4. Check minimum number of eventsNone |
2686 |
5. Include endpointsNone |
2686 |
6. Filter based on genotype QC (FinnGen only) |
2597 |
Control definitions (FinnGen only)
Extra metadata
Similar endpoints
↥List of similar endpoints to Bronchiectasis based on the number of shared cases.
Similar with more cases:
- Chronic lower respiratory diseases
- Excluding asthma or asthma-COPD overlap
- COPD differential diagnosis
- ILD differential diagnosis
- Diseases of the respiratory system
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 19660 | 10773 | 8661 |
Only index persons | 15964 | 9233 | 6731 |
Unadjusted period prevalence (%) | |||
Whole population | 0.28 | 0.31 | 0.24 |
Only index persons | 0.30 | 0.34 | 0.26 |
Median age at first event (years) | |||
Whole population | 64.04 | 63.59 | 64.67 |
Only index persons | 63.90 | 63.42 | 64.55 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 2597 | 1433 | 1164 |
Unadjusted period prevalence (%) | 0.57 | 0.56 | 0.58 |
Median age at first event (years) | 63.45 | 62.20 | 65.00 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint J10_BRONCHIECTASIS and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
J10_BRONCHIECTASIS | 1.545 [1.4, 1.7] | < 0.001 |
Birth year | 0.995 [0.99, 1.0] | 0.26 |
During the follow-up period (1.1.1998 — 31.12.2019), 1891 out of 7086 females with J10_BRONCHIECTASIS died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
J10_BRONCHIECTASIS | 1.732 [1.55, 1.94] | < 0.001 |
Birth year | 0.991 [0.98, 1.0] | 0.047 |
During the follow-up period (1.1.1998 — 31.12.2019), 2027 out of 5373 males with J10_BRONCHIECTASIS died.
Mortality risk
Mortality risk for people of age
years, who have J10_BRONCHIECTASIS.N-year risk | Females | Males |
---|---|---|
1 | 0.149% | 0.35% |
5 | 0.891% | 2.106% |
10 | 2.296% | 5.365% |
15 | 4.16% | 9.995% |
20 | 7.387% | 17.149% |
Relationships between endpoints
↥Index endpoint: J10_BRONCHIECTASIS – Bronchiectasis
GWS hits: 1