Lung Abscess: Solitary or multiple collections of PUS within the lung parenchyma as a result of infection by bacteria, protozoa, or other agents.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
60 |
4. Check minimum number of eventsNone |
60 |
5. Include endpointsNone |
60 |
6. Filter based on genotype QC (FinnGen only) |
58 |
Control definitions (FinnGen only)
Control exclude
J10_NECROTIC
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
J85
Name in latin
Abscessus mediastini
Similar endpoints
↥List of similar endpoints to
Abscess of mediastinum
based on the number of shared cases.
Similar with more cases:
- Suppurative and necrotic conditions of lower respiratory tract
- Diseases of the respiratory system
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 468 | 143 | 320 |
| Only index persons | 353 | 110 | 243 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.00 | 0.01 |
| Only index persons | 0.01 | 0.00 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 62.93 | 66.74 | 61.28 |
| Only index persons | 61.87 | 64.58 | 60.65 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 58 | 22 | 36 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.02 |
| Median age at first event (years) | 65.39 | 61.51 | 67.77 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint J10_ABSCMEDIASTINUM and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_ABSCMEDIASTINUM | 2.669 [1.97, 3.61] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 119 out of 240 males with J10_ABSCMEDIASTINUM died.
Mortality risk
Mortality risk for people of age
years, who have J10_ABSCMEDIASTINUM.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.478% |
| 5 | No data | 3.176% |
| 10 | No data | 7.433% |
| 15 | No data | 13.659% |
| 20 | No data | 21.813% |
Relationships between endpoints
↥Index endpoint: J10_ABSCMEDIASTINUM – Abscess of mediastinum
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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