Pasteurella hemorrhagic septicemia: Any of several bacterial diseases, usually caused by pasteurella multocida, marked by the presence of hemorrhagic areas in the subcutaneous tissues, serous membranes, muscles, lymph glands, and throughout the internal organs. The diseases primarily affect animals and rarely humans.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
62 |
4. Check minimum number of eventsNone |
62 |
5. Include endpointsNone |
62 |
6. Filter based on genotype QC (FinnGen only) |
59 |
Control definitions (FinnGen only)
Control exclude
ASTHMA_SEPTICHE_PNEUMONIA
Extra metadata
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
A41
Name in latin
Septic(h)aemia ab Haemophilo influenzae
Similar endpoints
↥List of similar endpoints to
Haemophilus septicemia
based on the number of shared cases.
Similar with more cases:
- Pneumonia derived septicemia
- Pneumonia derived septicemia
- Other septicaemia
- Septicaemia
- Explicit Sepsis
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 634 | 322 | 306 |
| Only index persons | 485 | 264 | 221 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 61.69 | 65.59 | 57.45 |
| Only index persons | 60.23 | 65.06 | 54.47 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 59 | 28 | 31 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.02 |
| Median age at first event (years) | 58.23 | 53.20 | 62.78 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint HAEMOPHIL_SEPTICHE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| HAEMOPHIL_SEPTICHE | 3.291 [1.69, 6.41] | < 0.001 |
| Birth year | 0.999 [0.99, 1.01] | 0.79 |
During the follow-up period (1.1.1998 — 31.12.2019), 77 out of 192 females with HAEMOPHIL_SEPTICHE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| HAEMOPHIL_SEPTICHE | 3.733 [1.8, 7.73] | < 0.001 |
| Birth year | 0.984 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 77 out of 182 males with HAEMOPHIL_SEPTICHE died.
Mortality risk
Mortality risk for people of age
years, who have HAEMOPHIL_SEPTICHE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.445% | 0.698% |
| 5 | 2.386% | 3.852% |
| 10 | 5.776% | 9.398% |
| 15 | 10.766% | 17.086% |
| 20 | 18.101% | 28.376% |
Relationships between endpoints
↥Index endpoint: HAEMOPHIL_SEPTICHE – Haemophilus septicemia
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data