No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
500 |
4. Check minimum number of eventsNone |
500 |
5. Include endpointsNone |
500 |
6. Filter based on genotype QC (FinnGen only) |
476 |
Control definitions (FinnGen only)
Control exclude
H8_INNER
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H81
Name in latin
Vertigo centralis
Similar endpoints
↥List of similar endpoints to
Vertigo of central origin
based on the number of shared cases.
Similar with more cases:
- Disorders of vestibular function (Vertigo)
- Diseases of inner ear
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4801 | 3024 | 1740 |
| Only index persons | 3769 | 2372 | 1397 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.09 | 0.05 |
| Only index persons | 0.07 | 0.09 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 70.36 | 71.94 | 67.46 |
| Only index persons | 66.62 | 67.92 | 64.42 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 476 | 286 | 190 |
| Unadjusted period prevalence (%) | 0.11 | 0.11 | 0.10 |
| Median age at first event (years) | 62.01 | 60.20 | 64.72 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint H8_VERTIGOCENT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_VERTIGOCENT | 1.227 [1.11, 1.36] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.01 |
During the follow-up period (1.1.1998 — 31.12.2019), 1126 out of 2537 females with H8_VERTIGOCENT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_VERTIGOCENT | 1.266 [1.1, 1.45] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.021 |
During the follow-up period (1.1.1998 — 31.12.2019), 670 out of 1498 males with H8_VERTIGOCENT died.
Mortality risk
Mortality risk for people of age
years, who have H8_VERTIGOCENT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.097% | 0.29% |
| 5 | 0.606% | 1.603% |
| 10 | 1.518% | 4.157% |
| 15 | 2.797% | 7.829% |
| 20 | 4.847% | 13.0% |
Relationships between endpoints
↥Index endpoint: H8_VERTIGOCENT – Vertigo of central origin
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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