No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
9262 |
4. Check minimum number of eventsNone |
9262 |
5. Include endpointsNone |
9262 |
6. Filter based on genotype QC (FinnGen only) |
8926 |
Control definitions (FinnGen only)
Control exclude
H8_OTHEREAR
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H93
Name in latin
Tinnitus (auris/aurium)
Similar endpoints
↥List of similar endpoints to
Tinnitus
based on the number of shared cases.
Similar with more cases:
- Other disorders of ear
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 61296 | 32184 | 28857 |
| Only index persons | 59727 | 31616 | 28111 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.86 | 0.92 | 0.81 |
| Only index persons | 1.12 | 1.16 | 1.07 |
| Median age at first event (years) | |||
| Whole population | 55.32 | 56.73 | 53.86 |
| Only index persons | 55.25 | 56.63 | 53.71 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 8926 | 5148 | 3778 |
| Unadjusted period prevalence (%) | 1.97 | 2.02 | 1.90 |
| Median age at first event (years) | 57.13 | 56.42 | 58.10 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H8_TINNITUS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_TINNITUS | 0.766 [0.69, 0.84] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.013 |
During the follow-up period (1.1.1998 — 31.12.2019), 2297 out of 27203 females with H8_TINNITUS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_TINNITUS | 0.731 [0.67, 0.8] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 2500 out of 24807 males with H8_TINNITUS died.
Mortality risk
Mortality risk for people of age
years, who have H8_TINNITUS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.067% | 0.142% |
| 5 | 0.368% | 0.869% |
| 10 | 0.959% | 2.177% |
| 15 | 1.757% | 4.097% |
| 20 | 3.146% | 7.19% |
Relationships between endpoints
↥Index endpoint: H8_TINNITUS – Tinnitus
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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