No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
89 |
4. Check minimum number of eventsNone |
89 |
5. Include endpointsNone |
89 |
6. Filter based on genotype QC (FinnGen only) |
88 |
Control definitions (FinnGen only)
Control exclude
H8_OTHEREAR
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H92
Name in latin
Otorrhoea
Similar endpoints
↥List of similar endpoints to
Otorrhoea
based on the number of shared cases.
Similar with more cases:
- Other disorders of ear
- Diseases of the ear and mastoid process
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1405 | 620 | 781 |
| Only index persons | 922 | 434 | 488 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.02 |
| Only index persons | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 14.43 | 23.40 | 7.15 |
| Only index persons | 38.46 | 44.95 | 32.70 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 88 | 59 | 29 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.01 |
| Median age at first event (years) | 53.90 | 50.75 | 60.31 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint H8_OTORRHOEA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_OTORRHOEA | 1.491 [1.02, 2.18] | 0.04 |
| Birth year | 0.997 [0.99, 1.01] | 0.447 |
During the follow-up period (1.1.1998 — 31.12.2019), 55 out of 558 females with H8_OTORRHOEA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_OTORRHOEA | 1.271 [0.9, 1.79] | 0.173 |
| Birth year | 0.988 [0.98, 1.0] | 0.014 |
During the follow-up period (1.1.1998 — 31.12.2019), 74 out of 707 males with H8_OTORRHOEA died.
Mortality risk
Mortality risk for people of age
years, who have H8_OTORRHOEA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.182% | 0.25% |
| 5 | 1.008% | 1.486% |
| 10 | 2.378% | 3.85% |
| 15 | 4.442% | 7.101% |
| 20 | 8.02% | 11.758% |
Relationships between endpoints
↥Index endpoint: H8_OTORRHOEA – Otorrhoea
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data