No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
200 |
4. Check minimum number of eventsNone |
200 |
5. Include endpointsNone |
200 |
6. Filter based on genotype QC (FinnGen only) |
192 |
Control definitions (FinnGen only)
Control exclude
H8_OTHEREAR
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H92
Name in latin
Otorrhagia
Similar endpoints
↥List of similar endpoints to
Otorrhagia
based on the number of shared cases.
Similar with more cases:
- Other disorders of ear
- Diseases of the ear and mastoid process
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1851 | 828 | 1014 |
| Only index persons | 1598 | 720 | 878 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.02 | 0.03 |
| Only index persons | 0.03 | 0.03 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 56.80 | 63.46 | 51.22 |
| Only index persons | 59.29 | 66.15 | 53.66 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 192 | 89 | 103 |
| Unadjusted period prevalence (%) | 0.04 | 0.03 | 0.05 |
| Median age at first event (years) | 63.17 | 63.31 | 63.04 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint H8_OTORRHAGIA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_OTORRHAGIA | 1.65 [1.23, 2.22] | 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.45 |
During the follow-up period (1.1.1998 — 31.12.2019), 153 out of 677 females with H8_OTORRHAGIA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_OTORRHAGIA | 2.165 [1.52, 3.07] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.012 |
During the follow-up period (1.1.1998 — 31.12.2019), 185 out of 847 males with H8_OTORRHAGIA died.
Mortality risk
Mortality risk for people of age
years, who have H8_OTORRHAGIA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.191% | 0.416% |
| 5 | 0.975% | 2.488% |
| 10 | 2.277% | 5.739% |
| 15 | 4.61% | 10.897% |
| 20 | 8.497% | 17.972% |
Relationships between endpoints
↥Index endpoint: H8_OTORRHAGIA – Otorrhagia
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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