quadriplegia: Paralysis of all four limbs. [database_cross_reference: NCIT:P378]
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2758 |
4. Check minimum number of eventsNone |
2758 |
5. Include endpointsNone |
2758 |
6. Filter based on genotype QC (FinnGen only) |
2646 |
Control definitions (FinnGen only)
Extra metadata
Similar endpoints
↥List of similar endpoints to Otalgia based on the number of shared cases.
Similar with more cases:
- Other disorders of ear
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 32065 | 19376 | 12536 |
Only index persons | 23581 | 15251 | 8330 |
Unadjusted period prevalence (%) | |||
Whole population | 0.47 | 0.55 | 0.35 |
Only index persons | 0.47 | 0.56 | 0.32 |
Median age at first event (years) | |||
Whole population | 20.62 | 26.65 | 11.14 |
Only index persons | 34.95 | 38.44 | 28.57 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 2646 | 1965 | 681 |
Unadjusted period prevalence (%) | 0.66 | 0.77 | 0.34 |
Median age at first event (years) | 52.72 | 51.33 | 56.74 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H8_OTALGIA and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
H8_OTALGIA | 0.943 [0.81, 1.1] | 0.442 |
Birth year | 0.995 [0.99, 1.0] | 0.29 |
During the follow-up period (1.1.1998 — 31.12.2019), 730 out of 15561 females with H8_OTALGIA died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
H8_OTALGIA | 0.972 [0.82, 1.16] | 0.753 |
Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 478 out of 9967 males with H8_OTALGIA died.
Mortality risk
Mortality risk for people of age
years, who have H8_OTALGIA.N-year risk | Females | Males |
---|---|---|
1 | 0.104% | 0.154% |
5 | 0.657% | 1.016% |
10 | 1.497% | 2.768% |
15 | 2.837% | 5.451% |
20 | 4.958% | 9.074% |
Relationships between endpoints
↥Index endpoint: H8_OTALGIA – Otalgia
GWS hits: -