No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
11234 |
4. Check minimum number of eventsNone |
11234 |
5. Include endpointsNone |
11234 |
6. Filter based on genotype QC (FinnGen only) |
10765 |
Control definitions (FinnGen only)
Control exclude
H8_MIDDLEMASTOID
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H65-H75
Name in latin
Otitis media non purulenta
Similar endpoints
↥List of similar endpoints to
Nonsuppurative otitis media
based on the number of shared cases.
Similar with more cases:
- Diseases of middle ear and mastoid
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 244297 | 102021 | 142055 |
| Only index persons | 195884 | 82644 | 113240 |
| Unadjusted period prevalence (%) | |||
| Whole population | 3.53 | 2.92 | 3.97 |
| Only index persons | 3.78 | 3.04 | 4.32 |
| Median age at first event (years) | |||
| Whole population | 2.64 | 2.86 | 2.41 |
| Only index persons | 2.91 | 3.24 | 2.67 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 10765 | 6339 | 4426 |
| Unadjusted period prevalence (%) | 2.38 | 2.49 | 2.22 |
| Median age at first event (years) | 5.49 | 5.24 | 5.85 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H8_NONSUPPNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_NONSUPPNAS | 1.352 [1.18, 1.55] | < 0.001 |
| Birth year | 0.999 [0.99, 1.01] | 0.839 |
During the follow-up period (1.1.1998 — 31.12.2019), 2508 out of 74097 females with H8_NONSUPPNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_NONSUPPNAS | 1.388 [1.21, 1.59] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.016 |
During the follow-up period (1.1.1998 — 31.12.2019), 2869 out of 99771 males with H8_NONSUPPNAS died.
Mortality risk
Mortality risk for people of age
years, who have H8_NONSUPPNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.158% | 0.261% |
| 5 | 0.948% | 1.545% |
| 10 | 2.324% | 3.972% |
| 15 | 4.35% | 7.726% |
| 20 | 7.699% | 12.941% |
Relationships between endpoints
↥Index endpoint: H8_NONSUPPNAS – Nonsuppurative otitis media
GWS hits: 5
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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