No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
145 |
4. Check minimum number of eventsNone |
145 |
5. Include endpointsNone |
145 |
6. Filter based on genotype QC (FinnGen only) |
139 |
Control definitions (FinnGen only)
Control exclude
H8_MIDDLEMASTOID
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H73
Name in latin
Myringitis chronica
Similar endpoints
↥List of similar endpoints to
Chronic myringitis
based on the number of shared cases.
Similar with more cases:
- Diseases of middle ear and mastoid
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1468 | 726 | 734 |
| Only index persons | 1375 | 692 | 683 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.02 |
| Only index persons | 0.03 | 0.03 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 43.87 | 44.67 | 43.07 |
| Only index persons | 44.96 | 45.66 | 44.24 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 139 | 77 | 62 |
| Unadjusted period prevalence (%) | 0.03 | 0.03 | 0.03 |
| Median age at first event (years) | 56.23 | 55.17 | 57.55 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint H8_MYRINGCHRON and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_MYRINGCHRON | 0.971 [0.69, 1.37] | 0.867 |
| Birth year | 0.995 [0.99, 1.0] | 0.274 |
During the follow-up period (1.1.1998 — 31.12.2019), 51 out of 610 females with H8_MYRINGCHRON died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_MYRINGCHRON | 0.866 [0.64, 1.18] | 0.359 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 53 out of 607 males with H8_MYRINGCHRON died.
Mortality risk
Mortality risk for people of age
years, who have H8_MYRINGCHRON.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.117% | 0.183% |
| 5 | 0.575% | 0.998% |
| 10 | 1.505% | 2.504% |
| 15 | 2.861% | 4.861% |
| 20 | 4.939% | 8.169% |
Relationships between endpoints
↥Index endpoint: H8_MYRINGCHRON – Chronic myringitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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