No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
230 |
4. Check minimum number of eventsNone |
230 |
5. Include endpointsNone |
230 |
6. Filter based on genotype QC (FinnGen only) |
223 |
Control definitions (FinnGen only)
Control exclude
H8_MIDDLEMASTOID
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H73
Name in latin
Myringitis acuta
Similar endpoints
↥List of similar endpoints to
Acute myringitis
based on the number of shared cases.
Similar with more cases:
- Diseases of middle ear and mastoid
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3427 | 1705 | 1712 |
| Only index persons | 2624 | 1359 | 1265 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.05 | 0.05 |
| Only index persons | 0.05 | 0.05 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 11.72 | 13.87 | 9.40 |
| Only index persons | 19.24 | 21.74 | 16.56 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 223 | 142 | 81 |
| Unadjusted period prevalence (%) | 0.05 | 0.06 | 0.04 |
| Median age at first event (years) | 39.72 | 36.85 | 44.75 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint H8_MYRINGACU and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_MYRINGACU | 1.323 [0.97, 1.81] | 0.079 |
| Birth year | 0.995 [0.99, 1.0] | 0.313 |
During the follow-up period (1.1.1998 — 31.12.2019), 58 out of 1464 females with H8_MYRINGACU died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_MYRINGACU | 1.3 [0.92, 1.83] | 0.133 |
| Birth year | 0.99 [0.98, 1.0] | 0.04 |
During the follow-up period (1.1.1998 — 31.12.2019), 52 out of 1363 males with H8_MYRINGACU died.
Mortality risk
Mortality risk for people of age
years, who have H8_MYRINGACU.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.129% | 0.354% |
| 5 | 0.737% | 1.732% |
| 10 | 2.045% | 4.315% |
| 15 | 4.011% | 8.126% |
| 20 | 6.719% | 13.886% |
Relationships between endpoints
↥Index endpoint: H8_MYRINGACU – Acute myringitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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