external ear disease: A disease involving the external ear. [database_cross_reference: MONDO:DesignPattern]
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1150 |
4. Check minimum number of eventsNone |
1150 |
5. Include endpointsNone |
1150 |
6. Filter based on genotype QC (FinnGen only) |
1107 |
Control definitions (FinnGen only)
Extra metadata
Similar endpoints
↥List of similar endpoints to Other specified disorders of external ear based on the number of shared cases.
Similar with more cases:
- Diseases of external ear
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 8281 | 2364 | 5883 |
Only index persons | 7659 | 2206 | 5453 |
Unadjusted period prevalence (%) | |||
Whole population | 0.14 | 0.07 | 0.16 |
Only index persons | 0.17 | 0.08 | 0.21 |
Median age at first event (years) | |||
Whole population | 54.74 | 53.01 | 55.43 |
Only index persons | 55.12 | 53.64 | 55.72 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 1107 | 276 | 831 |
Unadjusted period prevalence (%) | 0.34 | 0.11 | 0.42 |
Median age at first event (years) | 59.82 | 58.52 | 60.25 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H8_EXTDISNAS and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
H8_EXTDISNAS | 1.237 [1.0, 1.53] | 0.05 |
Birth year | 0.992 [0.98, 1.0] | 0.063 |
During the follow-up period (1.1.1998 — 31.12.2019), 211 out of 1882 females with H8_EXTDISNAS died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
H8_EXTDISNAS | 0.863 [0.76, 0.98] | 0.02 |
Birth year | 0.988 [0.98, 1.0] | 0.016 |
During the follow-up period (1.1.1998 — 31.12.2019), 652 out of 4632 males with H8_EXTDISNAS died.
Mortality risk
Mortality risk for people of age
years, who have H8_EXTDISNAS.N-year risk | Females | Males |
---|---|---|
1 | 0.1% | 0.141% |
5 | 0.707% | 1.015% |
10 | 1.709% | 2.44% |
15 | 3.23% | 4.766% |
20 | 5.448% | 8.588% |
Relationships between endpoints
↥Index endpoint: H8_EXTDISNAS – Other specified disorders of external ear
GWS hits: -