auditory system disease: Pathological processes of the ear, the hearing, and the equilibrium system of the body.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1023 |
4. Check minimum number of eventsNone |
1023 |
5. Include endpointsNone |
1023 |
6. Filter based on genotype QC (FinnGen only) |
991 |
Control definitions (FinnGen only)
Extra metadata
Similar endpoints
↥List of similar endpoints to Disorder of external ear, unspecified based on the number of shared cases.
Similar with more cases:
- Diseases of external ear
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 7369 | 3573 | 3766 |
Only index persons | 7023 | 3453 | 3570 |
Unadjusted period prevalence (%) | |||
Whole population | 0.10 | 0.10 | 0.11 |
Only index persons | 0.13 | 0.13 | 0.14 |
Median age at first event (years) | |||
Whole population | 57.40 | 57.69 | 57.22 |
Only index persons | 57.52 | 57.75 | 57.29 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 991 | 517 | 474 |
Unadjusted period prevalence (%) | 0.22 | 0.20 | 0.24 |
Median age at first event (years) | 58.72 | 56.65 | 60.98 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H8_EXTDISINOTH and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
H8_EXTDISINOTH | 1.404 [1.19, 1.66] | < 0.001 |
Birth year | 0.998 [0.99, 1.01] | 0.619 |
During the follow-up period (1.1.1998 — 31.12.2019), 419 out of 2954 females with H8_EXTDISINOTH died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
H8_EXTDISINOTH | 1.515 [1.27, 1.8] | < 0.001 |
Birth year | 0.987 [0.98, 1.0] | 0.007 |
During the follow-up period (1.1.1998 — 31.12.2019), 517 out of 3092 males with H8_EXTDISINOTH died.
Mortality risk
Mortality risk for people of age
years, who have H8_EXTDISINOTH.N-year risk | Females | Males |
---|---|---|
1 | 0.167% | 0.355% |
5 | 0.973% | 1.728% |
10 | 2.414% | 4.346% |
15 | 4.32% | 8.045% |
20 | 7.788% | 13.438% |
Relationships between endpoints
↥Index endpoint: H8_EXTDISINOTH – Disorder of external ear, unspecified
GWS hits: 1