auditory system disease: Pathological processes of the ear, the hearing, and the equilibrium system of the body.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
938 |
4. Check minimum number of eventsNone |
938 |
5. Include endpointsNone |
938 |
6. Filter based on genotype QC (FinnGen only) |
897 |
Control definitions (FinnGen only)
Extra metadata
Similar endpoints
↥List of similar endpoints to Other disorders of Eustachian tube based on the number of shared cases.
Similar with more cases:
- Diseases of middle ear and mastoid
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 6062 | 3566 | 2467 |
Only index persons | 5812 | 3458 | 2354 |
Unadjusted period prevalence (%) | |||
Whole population | 0.09 | 0.10 | 0.07 |
Only index persons | 0.11 | 0.13 | 0.09 |
Median age at first event (years) | |||
Whole population | 48.24 | 47.07 | 49.93 |
Only index persons | 48.07 | 46.99 | 49.66 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 897 | 580 | 317 |
Unadjusted period prevalence (%) | 0.20 | 0.23 | 0.16 |
Median age at first event (years) | 54.92 | 51.45 | 61.29 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H8_EUSTNAS and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
H8_EUSTNAS | 1.042 [0.88, 1.23] | 0.633 |
Birth year | 0.993 [0.98, 1.0] | 0.101 |
During the follow-up period (1.1.1998 — 31.12.2019), 209 out of 2905 females with H8_EUSTNAS died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
H8_EUSTNAS | 1.333 [1.11, 1.6] | 0.002 |
Birth year | 0.985 [0.98, 0.99] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 270 out of 1926 males with H8_EUSTNAS died.
Mortality risk
Mortality risk for people of age
years, who have H8_EUSTNAS.N-year risk | Females | Males |
---|---|---|
1 | 0.114% | 0.267% |
5 | 0.58% | 1.539% |
10 | 1.468% | 3.684% |
15 | 2.676% | 6.729% |
20 | 4.803% | 11.652% |
Relationships between endpoints
↥Index endpoint: H8_EUSTNAS – Other disorders of Eustachian tube
GWS hits: 2