Other specified/unspecified disorders of ear

H8_EARNAS

auditory system disease: Pathological processes of the ear, the hearing, and the equilibrium system of the body.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H93.8, H93.9
  • Hospital discharge: ICD-9 388[8-9]
  • Cause of death: ICD-10 H93.8, H93.9
  • Cause of death: ICD-9 388[8-9]

2 out of 7 registries used, show all original rules.

87

4. Check minimum number of events

None

87

5. Include endpoints

None

87

6. Filter based on genotype QC (FinnGen only)

83

Control definitions (FinnGen only)

Control exclude H8_OTHEREAR

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 846 451 389
Only index persons 716 406 310
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 46.76 50.76 41.95
Only index persons 48.46 51.62 44.31

-FinnGen-

Key figures

All Female Male
Number of individuals 83 58 25
Unadjusted period prevalence (%) 0.02 0.02 0.01
Median age at first event (years) 52.04 52.90 50.06

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

Association

Association between endpoint H8_EARNAS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have H8_EARNAS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: H8_EARNAS – Other specified/unspecified disorders of ear

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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