auditory system disease: Pathological processes of the ear, the hearing, and the equilibrium system of the body.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
352 |
4. Check minimum number of eventsNone |
352 |
5. Include endpointsNone |
352 |
6. Filter based on genotype QC (FinnGen only) |
334 |
Control definitions (FinnGen only)
Control exclude
H8_OTHEREAR
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H93
Name in latin
Aliae perceptiones auditoriae abnormes
Similar endpoints
↥List of similar endpoints to
Other abnormal auditory perceptions
based on the number of shared cases.
Similar with more cases:
- Other disorders of ear
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2549 | 1593 | 947 |
| Only index persons | 2466 | 1555 | 911 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.05 | 0.03 |
| Only index persons | 0.05 | 0.06 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 46.50 | 48.98 | 42.40 |
| Only index persons | 46.89 | 49.24 | 42.89 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 334 | 242 | 92 |
| Unadjusted period prevalence (%) | 0.08 | 0.10 | 0.05 |
| Median age at first event (years) | 51.28 | 50.49 | 53.38 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint H8_ABNAUDPER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_ABNAUDPER | 0.748 [0.58, 0.96] | 0.025 |
| Birth year | 0.998 [0.99, 1.01] | 0.628 |
During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 1328 females with H8_ABNAUDPER died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have H8_ABNAUDPER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.074% | No data |
| 5 | 0.432% | No data |
| 10 | 1.122% | No data |
| 15 | 2.294% | No data |
| 20 | 4.246% | No data |
Relationships between endpoints
↥Index endpoint: H8_ABNAUDPER – Other abnormal auditory perceptions
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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