eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
15560 |
4. Check minimum number of eventsNone |
15560 |
5. Include endpointsNone |
15560 |
6. Filter based on genotype QC (FinnGen only) |
15092 |
Control definitions (FinnGen only)
Extra metadata
Similar endpoints
↥List of similar endpoints to Other and unspecified disorders of vitreous body based on the number of shared cases.
Similar with more cases:
- Disorders of vitreous body
- Disorders of vitreous body and globe
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 98239 | 65258 | 32715 |
Only index persons | 95799 | 64131 | 31668 |
Unadjusted period prevalence (%) | |||
Whole population | 1.55 | 1.87 | 0.91 |
Only index persons | 1.98 | 2.36 | 1.21 |
Median age at first event (years) | |||
Whole population | 63.92 | 63.29 | 65.22 |
Only index persons | 63.87 | 63.24 | 65.16 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 15092 | 10103 | 4989 |
Unadjusted period prevalence (%) | 3.48 | 3.97 | 2.51 |
Median age at first event (years) | 63.87 | 62.71 | 66.23 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H7_VITROTH and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
H7_VITROTH | 0.718 [0.65, 0.79] | < 0.001 |
Birth year | 0.996 [0.99, 1.0] | 0.28 |
During the follow-up period (1.1.1998 — 31.12.2019), 4325 out of 53822 females with H7_VITROTH died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
H7_VITROTH | 0.703 [0.63, 0.78] | < 0.001 |
Birth year | 0.986 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 3287 out of 26151 males with H7_VITROTH died.
Mortality risk
Mortality risk for people of age
years, who have H7_VITROTH.N-year risk | Females | Males |
---|---|---|
1 | 0.063% | 0.154% |
5 | 0.354% | 0.828% |
10 | 1.011% | 2.072% |
15 | 2.029% | 3.901% |
20 | 3.577% | 6.741% |
Relationships between endpoints
↥Index endpoint: H7_VITROTH – Other and unspecified disorders of vitreous body
GWS hits: -