No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1273 |
4. Check minimum number of eventsNone |
1273 |
5. Include endpointsNone |
1273 |
6. Filter based on genotype QC (FinnGen only) |
1232 |
Control definitions (FinnGen only)
Control exclude
H7_VITREOUS
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H43
Name in latin
Opacitates corporis vitrei
Similar endpoints
↥List of similar endpoints to
Other vitreous opacities
based on the number of shared cases.
Similar with more cases:
- Disorders of vitreous body
- Disorders of vitreous body and globe
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 9084 | 5174 | 3874 |
| Only index persons | 8664 | 4997 | 3667 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.13 | 0.15 | 0.11 |
| Only index persons | 0.17 | 0.18 | 0.14 |
| Median age at first event (years) | |||
| Whole population | 62.97 | 61.94 | 64.41 |
| Only index persons | 62.64 | 61.65 | 64.00 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1232 | 716 | 516 |
| Unadjusted period prevalence (%) | 0.27 | 0.28 | 0.26 |
| Median age at first event (years) | 62.76 | 59.74 | 66.95 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H7_VITROPACIT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_VITROPACIT | 0.973 [0.87, 1.09] | 0.646 |
| Birth year | 0.995 [0.99, 1.0] | 0.253 |
During the follow-up period (1.1.1998 — 31.12.2019), 644 out of 4409 females with H7_VITROPACIT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_VITROPACIT | 0.898 [0.79, 1.02] | 0.095 |
| Birth year | 0.985 [0.98, 0.99] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 756 out of 3373 males with H7_VITROPACIT died.
Mortality risk
Mortality risk for people of age
years, who have H7_VITROPACIT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.087% | 0.164% |
| 5 | 0.541% | 1.043% |
| 10 | 1.374% | 2.506% |
| 15 | 2.673% | 4.825% |
| 20 | 4.5% | 8.075% |
Relationships between endpoints
↥Index endpoint: H7_VITROPACIT – Other vitreous opacities
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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