eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
264 |
4. Check minimum number of eventsNone |
264 |
5. Include endpointsNone |
264 |
6. Filter based on genotype QC (FinnGen only) |
253 |
Control definitions (FinnGen only)
Extra metadata
Similar endpoints
↥List of similar endpoints to Crystalline deposits in vitreous body based on the number of shared cases.
Similar with more cases:
- Disorders of vitreous body
- Disorders of vitreous body and globe
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 1754 | 700 | 1049 |
Only index persons | 1640 | 667 | 973 |
Unadjusted period prevalence (%) | |||
Whole population | 0.03 | 0.02 | 0.03 |
Only index persons | 0.03 | 0.02 | 0.04 |
Median age at first event (years) | |||
Whole population | 71.12 | 69.89 | 71.95 |
Only index persons | 70.79 | 69.70 | 71.54 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 253 | 98 | 155 |
Unadjusted period prevalence (%) | 0.06 | 0.04 | 0.08 |
Median age at first event (years) | 68.71 | 65.39 | 70.82 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H7_VITRCRYSTAL and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
H7_VITRCRYSTAL | 0.983 [0.8, 1.21] | 0.868 |
Birth year | 0.996 [0.99, 1.0] | 0.342 |
During the follow-up period (1.1.1998 — 31.12.2019), 133 out of 603 females with H7_VITRCRYSTAL died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
H7_VITRCRYSTAL | 0.981 [0.8, 1.2] | 0.852 |
Birth year | 0.989 [0.98, 1.0] | 0.021 |
During the follow-up period (1.1.1998 — 31.12.2019), 251 out of 834 males with H7_VITRCRYSTAL died.
Mortality risk
Mortality risk for people of age
years, who have H7_VITRCRYSTAL.N-year risk | Females | Males |
---|---|---|
1 | 0.063% | 0.173% |
5 | 0.566% | 1.147% |
10 | 1.412% | 2.925% |
15 | 2.787% | 5.421% |
20 | 4.935% | 9.54% |
Relationships between endpoints
↥Index endpoint: H7_VITRCRYSTAL – Crystalline deposits in vitreous body
GWS hits: -