No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2984 |
4. Check minimum number of eventsNone |
2984 |
5. Include endpointsNone |
2984 |
6. Filter based on genotype QC (FinnGen only) |
2885 |
Control definitions (FinnGen only)
Control exclude
H7_VISUALDISTBLIND
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H53
Name in latin
Defectus campi visualis
Similar endpoints
↥List of similar endpoints to
Visual field defects
based on the number of shared cases.
Similar with more cases:
- Visual disturbances
- Visual disturbances and blindness
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 23456 | 11336 | 11957 |
| Only index persons | 21057 | 10440 | 10617 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.33 | 0.32 | 0.33 |
| Only index persons | 0.39 | 0.38 | 0.41 |
| Median age at first event (years) | |||
| Whole population | 61.46 | 60.49 | 62.29 |
| Only index persons | 60.42 | 59.50 | 61.34 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2885 | 1468 | 1417 |
| Unadjusted period prevalence (%) | 0.64 | 0.58 | 0.71 |
| Median age at first event (years) | 60.98 | 56.97 | 65.14 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H7_VISFIELDDEF and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_VISFIELDDEF | 1.669 [1.52, 1.83] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.15 |
During the follow-up period (1.1.1998 — 31.12.2019), 2621 out of 10302 females with H7_VISFIELDDEF died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_VISFIELDDEF | 1.77 [1.62, 1.94] | < 0.001 |
| Birth year | 0.983 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 3731 out of 10733 males with H7_VISFIELDDEF died.
Mortality risk
Mortality risk for people of age
years, who have H7_VISFIELDDEF.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.172% | 0.307% |
| 5 | 0.864% | 1.93% |
| 10 | 2.355% | 4.547% |
| 15 | 4.659% | 8.466% |
| 20 | 7.991% | 14.145% |
Relationships between endpoints
↥Index endpoint: H7_VISFIELDDEF – Visual field defects
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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