No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
377 |
4. Check minimum number of eventsNone |
377 |
5. Include endpointsNone |
377 |
6. Filter based on genotype QC (FinnGen only) |
359 |
Control definitions (FinnGen only)
Control exclude
H7_OCUMUSCLE
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Other specified and unspecified strabismus
based on the number of shared cases.
Similar with more cases:
- Other strabismus
- Strabismus
- Disorders of ocular muscles, binocular movement, accommodation and refraction
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4547 | 2406 | 2136 |
| Only index persons | 3496 | 1882 | 1614 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.07 | 0.06 |
| Only index persons | 0.07 | 0.07 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 9.45 | 11.12 | 7.46 |
| Only index persons | 16.21 | 20.13 | 11.64 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 359 | 227 | 132 |
| Unadjusted period prevalence (%) | 0.08 | 0.09 | 0.07 |
| Median age at first event (years) | 42.07 | 41.56 | 42.95 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint H7_STRABNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_STRABNAS | 1.175 [0.87, 1.58] | 0.284 |
| Birth year | 0.994 [0.99, 1.0] | 0.171 |
During the follow-up period (1.1.1998 — 31.12.2019), 80 out of 1777 females with H7_STRABNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_STRABNAS | 1.232 [0.89, 1.7] | 0.202 |
| Birth year | 0.987 [0.98, 1.0] | 0.016 |
During the follow-up period (1.1.1998 — 31.12.2019), 75 out of 1539 males with H7_STRABNAS died.
Mortality risk
Mortality risk for people of age
years, who have H7_STRABNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.091% | 0.215% |
| 5 | 0.655% | 1.266% |
| 10 | 1.807% | 3.642% |
| 15 | 3.292% | 7.24% |
| 20 | 5.626% | 11.799% |
Relationships between endpoints
↥Index endpoint: H7_STRABNAS – Other specified and unspecified strabismus
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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