No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
159 |
4. Check minimum number of eventsNone |
159 |
5. Include endpointsNone |
159 |
6. Filter based on genotype QC (FinnGen only) |
156 |
Control definitions (FinnGen only)
Control exclude
H7_VITREOUS
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF6
Similar endpoints
↥List of similar endpoints to
Other endophthalmitis
based on the number of shared cases.
Similar with more cases:
- Disorders of globe
- Disorders of vitreous body and globe
- Diseases of the eye and adnexa
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1770 | 938 | 814 |
| Only index persons | 1405 | 776 | 629 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.03 | 0.02 |
| Only index persons | 0.03 | 0.03 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 66.80 | 71.11 | 61.85 |
| Only index persons | 65.42 | 70.24 | 59.47 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 156 | 85 | 71 |
| Unadjusted period prevalence (%) | 0.03 | 0.03 | 0.04 |
| Median age at first event (years) | 60.44 | 59.02 | 62.15 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint H7_OTHENDOPHTHALMITIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_OTHENDOPHTHALMITIS | 1.387 [1.15, 1.67] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.049 |
During the follow-up period (1.1.1998 — 31.12.2019), 280 out of 691 females with H7_OTHENDOPHTHALMITIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_OTHENDOPHTHALMITIS | 1.786 [1.39, 2.3] | < 0.001 |
| Birth year | 0.983 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 230 out of 557 males with H7_OTHENDOPHTHALMITIS died.
Mortality risk
Mortality risk for people of age
years, who have H7_OTHENDOPHTHALMITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.091% | 0.253% |
| 5 | 0.739% | 1.803% |
| 10 | 1.913% | 4.433% |
| 15 | 3.556% | 8.403% |
| 20 | 6.099% | 13.372% |
Relationships between endpoints
↥Index endpoint: H7_OTHENDOPHTHALMITIS – Other endophthalmitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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