No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
151 |
4. Check minimum number of eventsNone |
151 |
5. Include endpointsNone |
151 |
6. Filter based on genotype QC (FinnGen only) |
144 |
Control definitions (FinnGen only)
Control exclude
H7_VISUALDISTBLIND
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H54
Name in latin
Amblyopia non specificata oculorum amborum
Similar endpoints
↥List of similar endpoints to
Mild or no visual impairment, binocular
based on the number of shared cases.
Similar with more cases:
- Visual impairment including blindness (binocular or monocular)
- Visual disturbances and blindness
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1613 | 870 | 732 |
| Only index persons | 1433 | 791 | 642 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.02 |
| Only index persons | 0.03 | 0.03 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 42.74 | 48.39 | 35.96 |
| Only index persons | 44.24 | 49.24 | 38.09 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 144 | 97 | 47 |
| Unadjusted period prevalence (%) | 0.03 | 0.04 | 0.02 |
| Median age at first event (years) | 52.93 | 49.88 | 59.21 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint H7_MILDVISIMPBINOC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_MILDVISIMPBINOC | 1.814 [1.3, 2.54] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.541 |
During the follow-up period (1.1.1998 — 31.12.2019), 182 out of 791 females with H7_MILDVISIMPBINOC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_MILDVISIMPBINOC | 2.239 [1.54, 3.26] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 181 out of 685 males with H7_MILDVISIMPBINOC died.
Mortality risk
Mortality risk for people of age
years, who have H7_MILDVISIMPBINOC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.192% | 0.38% |
| 5 | 1.068% | 2.285% |
| 10 | 2.739% | 5.686% |
| 15 | 5.429% | 11.097% |
| 20 | 9.766% | 18.066% |
Relationships between endpoints
↥Index endpoint: H7_MILDVISIMPBINOC – Mild or no visual impairment, binocular
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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