glaucoma: Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
203 |
4. Check minimum number of eventsNone |
203 |
5. Include endpointsNone |
203 |
6. Filter based on genotype QC (FinnGen only) |
197 |
Control definitions (FinnGen only)
Control exclude
H7_GLAUCOMA
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H40
Name in latin
Glaucoma [secundarium] posttraumaticum
Similar endpoints
↥List of similar endpoints to
Glaucoma secondary to eye trauma
based on the number of shared cases.
Similar with more cases:
- Glaucoma
- Diseases of the eye and adnexa
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2393 | 862 | 1511 |
| Only index persons | 2107 | 772 | 1335 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.02 | 0.04 |
| Only index persons | 0.04 | 0.03 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 61.99 | 69.56 | 57.65 |
| Only index persons | 60.89 | 68.48 | 56.50 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 197 | 76 | 121 |
| Unadjusted period prevalence (%) | 0.05 | 0.03 | 0.06 |
| Median age at first event (years) | 60.98 | 58.27 | 62.69 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint H7_GLAUCSECTRAUMA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_GLAUCSECTRAUMA | 1.083 [0.92, 1.27] | 0.327 |
| Birth year | 0.994 [0.99, 1.0] | 0.134 |
During the follow-up period (1.1.1998 — 31.12.2019), 277 out of 736 females with H7_GLAUCSECTRAUMA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_GLAUCSECTRAUMA | 1.166 [0.99, 1.37] | 0.061 |
| Birth year | 0.984 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 310 out of 1144 males with H7_GLAUCSECTRAUMA died.
Mortality risk
Mortality risk for people of age
years, who have H7_GLAUCSECTRAUMA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.096% | 0.217% |
| 5 | 0.64% | 1.213% |
| 10 | 1.766% | 3.075% |
| 15 | 3.328% | 5.942% |
| 20 | 5.542% | 9.904% |
Relationships between endpoints
↥Index endpoint: H7_GLAUCSECTRAUMA – Glaucoma secondary to eye trauma
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data