No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1805 |
4. Check minimum number of eventsNone |
1805 |
5. Include endpointsNone |
1805 |
6. Filter based on genotype QC (FinnGen only) |
1744 |
Control definitions (FinnGen only)
Control exclude
H7_SCLERACORNEA
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H15
Name in latin
Episcleritis
Similar endpoints
↥List of similar endpoints to
Episcleritis
based on the number of shared cases.
Similar with more cases:
- Scleritis and episcleritis
- Disorders of sclera, cornea, iris and ciliary body
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 12330 | 7764 | 4495 |
| Only index persons | 11967 | 7599 | 4368 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.19 | 0.22 | 0.13 |
| Only index persons | 0.24 | 0.28 | 0.17 |
| Median age at first event (years) | |||
| Whole population | 46.37 | 47.31 | 44.90 |
| Only index persons | 46.22 | 47.12 | 44.66 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1744 | 1229 | 515 |
| Unadjusted period prevalence (%) | 0.42 | 0.48 | 0.26 |
| Median age at first event (years) | 48.64 | 47.57 | 51.18 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H7_EPISCLERITIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_EPISCLERITIS | 0.976 [0.86, 1.11] | 0.716 |
| Birth year | 0.995 [0.99, 1.0] | 0.202 |
During the follow-up period (1.1.1998 — 31.12.2019), 401 out of 6850 females with H7_EPISCLERITIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_EPISCLERITIS | 0.891 [0.78, 1.02] | 0.088 |
| Birth year | 0.983 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 333 out of 3989 males with H7_EPISCLERITIS died.
Mortality risk
Mortality risk for people of age
years, who have H7_EPISCLERITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.079% | 0.105% |
| 5 | 0.549% | 0.867% |
| 10 | 1.368% | 2.199% |
| 15 | 2.618% | 4.184% |
| 20 | 4.691% | 7.167% |
Relationships between endpoints
↥Index endpoint: H7_EPISCLERITIS – Episcleritis
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data