No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1001 |
4. Check minimum number of eventsNone |
1001 |
5. Include endpointsNone |
1001 |
6. Filter based on genotype QC (FinnGen only) |
961 |
Control definitions (FinnGen only)
Control exclude
H7_CONJUNCTIVA
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H10
Name in latin
Conjunctivitis chronica
Similar endpoints
↥List of similar endpoints to
Chronic conjunctivitis
based on the number of shared cases.
Similar with more cases:
- Conjunctivitis
- Disorders of conjunctiva
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 8152 | 4892 | 3233 |
| Only index persons | 7374 | 4515 | 2859 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.14 | 0.09 |
| Only index persons | 0.14 | 0.17 | 0.11 |
| Median age at first event (years) | |||
| Whole population | 38.99 | 44.07 | 31.30 |
| Only index persons | 40.61 | 44.61 | 34.30 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 961 | 674 | 287 |
| Unadjusted period prevalence (%) | 0.23 | 0.26 | 0.14 |
| Median age at first event (years) | 48.27 | 48.31 | 48.18 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H7_CONJUNCTIVITISCHRON and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CONJUNCTIVITISCHRON | 1.053 [0.93, 1.19] | 0.416 |
| Birth year | 0.995 [0.99, 1.0] | 0.315 |
During the follow-up period (1.1.1998 — 31.12.2019), 451 out of 4367 females with H7_CONJUNCTIVITISCHRON died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CONJUNCTIVITISCHRON | 1.056 [0.9, 1.23] | 0.494 |
| Birth year | 0.986 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 290 out of 2698 males with H7_CONJUNCTIVITISCHRON died.
Mortality risk
Mortality risk for people of age
years, who have H7_CONJUNCTIVITISCHRON.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.113% | 0.184% |
| 5 | 0.617% | 1.142% |
| 10 | 1.576% | 2.972% |
| 15 | 2.77% | 5.727% |
| 20 | 5.35% | 9.739% |
Relationships between endpoints
↥Index endpoint: H7_CONJUNCTIVITISCHRON – Chronic conjunctivitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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