≡ Risteys
FG R11 + FR

Documentation Changelog GitHub Contact & Feedback

Chalazion

DOID EFO Endpoint Browser PheWeb

H7_CHALAZION

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H00.1
  • Hospital discharge: ICD-9 — 3732
  • Hospital discharge: ICD-8 — 3780
  • Cause of death: ICD-10 — H00.1
  • Cause of death: ICD-9 — 3732
  • Cause of death: ICD-8 — 3780

2 out of 7 registries used, show all original rules.

4345

4. Check minimum number of events

None

4345

5. Include endpoints

None

4345

6. Filter based on genotype QC (FinnGen only)

4177

Control definitions (FinnGen only)

Control exclude H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H00
Name in latin Chalazion

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 41962 22168 19588
Only index persons 39333 21012 18321
Unadjusted period prevalence (%)
Whole population 0.59 0.63 0.55
Only index persons 0.74 0.77 0.70
Median age at first event (years)
Whole population 42.34 41.84 42.98
Only index persons 42.78 42.32 43.31

-FinnGen-

Key figures

All Female Male
Number of individuals 4177 2418 1759
Unadjusted period prevalence (%) 0.92 0.95 0.88
Median age at first event (years) 49.27 47.20 52.13

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

↥

Association

Association between endpoint H7_CHALAZION and mortality.

Females

Parameter HR [95% CI] p-value
H7_CHALAZION 0.864 [0.78, 0.96] 0.005
Birth year 0.99 [0.98, 1.0] 0.025

During the follow-up period (1.1.1998 — 31.12.2019), 1487 out of 19433 females with H7_CHALAZION died.

Males

Parameter HR [95% CI] p-value
H7_CHALAZION 0.841 [0.77, 0.92] < 0.001
Birth year 0.989 [0.98, 1.0] 0.018

During the follow-up period (1.1.1998 — 31.12.2019), 1880 out of 17221 males with H7_CHALAZION died.

Mortality risk

Mortality risk for people of age

years, who have H7_CHALAZION.

N-year risk Females Males
1 0.045% 0.174%
5 0.42% 1.046%
10 1.075% 2.673%
15 2.027% 5.117%
20 3.582% 8.531%

Relationships between endpoints

↥

Index endpoint: H7_CHALAZION – Chalazion

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data