No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
442 |
4. Check minimum number of eventsNone |
442 |
5. Include endpointsNone |
442 |
6. Filter based on genotype QC (FinnGen only) |
429 |
Control definitions (FinnGen only)
Control exclude
H7_VISUALDISTBLIND
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H53
Name in latin
Aliae perturbationes visus binocularis
Similar endpoints
↥List of similar endpoints to
Other disorders of binocular vision
based on the number of shared cases.
Similar with more cases:
- Visual disturbances
- Visual disturbances and blindness
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4069 | 2676 | 1389 |
| Only index persons | 3914 | 2593 | 1321 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.08 | 0.04 |
| Only index persons | 0.08 | 0.10 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 24.72 | 24.46 | 25.21 |
| Only index persons | 25.18 | 24.84 | 25.85 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 429 | 319 | 110 |
| Unadjusted period prevalence (%) | 0.11 | 0.13 | 0.06 |
| Median age at first event (years) | 35.29 | 32.22 | 44.18 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint H7_BINODISTOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_BINODISTOTH | 1.046 [0.84, 1.31] | 0.695 |
| Birth year | 0.997 [0.99, 1.01] | 0.575 |
During the follow-up period (1.1.1998 — 31.12.2019), 105 out of 2492 females with H7_BINODISTOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_BINODISTOTH | 1.139 [0.89, 1.45] | 0.291 |
| Birth year | 0.988 [0.98, 1.0] | 0.013 |
During the follow-up period (1.1.1998 — 31.12.2019), 93 out of 1296 males with H7_BINODISTOTH died.
Mortality risk
Mortality risk for people of age
years, who have H7_BINODISTOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.112% | 0.227% |
| 5 | 0.569% | 1.355% |
| 10 | 1.518% | 3.457% |
| 15 | 3.118% | 6.739% |
| 20 | 5.849% | 11.563% |
Relationships between endpoints
↥Index endpoint: H7_BINODISTOTH – Other disorders of binocular vision
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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