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Lesion of ulnar nerve

DOID EFO Endpoint Browser PheWeb

G6_ULLNLE

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — G56.2
  • Hospital discharge: ICD-9 — 3542
  • Hospital discharge: ICD-8 — 35700
  • Cause of death: ICD-10 — G56.2
  • Cause of death: ICD-9 — 3542
  • Cause of death: ICD-8 — 35700

2 out of 7 registries used, show all original rules.

5332

4. Check minimum number of events

None

5332

5. Include endpoints

None

5332

6. Filter based on genotype QC (FinnGen only)

5155

Control definitions (FinnGen only)

Control exclude G6_NERPLEX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G56
Name in latin Morbositas nervi ulnaris

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 39329 16305 22788
Only index persons 36474 15571 20903
Unadjusted period prevalence (%)
Whole population 0.56 0.47 0.64
Only index persons 0.70 0.57 0.80
Median age at first event (years)
Whole population 51.48 51.09 51.77
Only index persons 51.16 50.77 51.45

-FinnGen-

Key figures

All Female Male
Number of individuals 5155 2383 2772
Unadjusted period prevalence (%) 1.18 0.94 1.39
Median age at first event (years) 52.59 50.31 54.55

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Association

Association between endpoint G6_ULLNLE and mortality.

Females

Parameter HR [95% CI] p-value
G6_ULLNLE 1.448 [1.3, 1.62] < 0.001
Birth year 0.995 [0.99, 1.0] 0.247

During the follow-up period (1.1.1998 — 31.12.2019), 1320 out of 12530 females with G6_ULLNLE died.

Males

Parameter HR [95% CI] p-value
G6_ULLNLE 1.392 [1.27, 1.53] < 0.001
Birth year 0.988 [0.98, 1.0] 0.01

During the follow-up period (1.1.1998 — 31.12.2019), 2780 out of 17326 males with G6_ULLNLE died.

Mortality risk

Mortality risk for people of age

years, who have G6_ULLNLE.

N-year risk Females Males
1 0.082% 0.283%
5 0.695% 1.779%
10 1.949% 4.268%
15 3.738% 8.303%
20 6.725% 13.774%

Relationships between endpoints

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Index endpoint: G6_ULLNLE – Lesion of ulnar nerve

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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