No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2149 |
4. Check minimum number of eventsNone |
2149 |
5. Include endpointsNone |
2149 |
6. Filter based on genotype QC (FinnGen only) |
2075 |
Control definitions (FinnGen only)
Control exclude
G6_NERPLEX
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G57
Name in latin
Morbositas nervi plantaris (medialis)
Similar endpoints
↥List of similar endpoints to
Lesion of plantar nerve
based on the number of shared cases.
Similar with more cases:
- Nerve, nerve root and plexus disorders
- Neurological diseases
- Neurological diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 12606 | 9829 | 2737 |
| Only index persons | 12153 | 9563 | 2590 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.24 | 0.28 | 0.08 |
| Only index persons | 0.30 | 0.35 | 0.10 |
| Median age at first event (years) | |||
| Whole population | 53.83 | 53.96 | 53.40 |
| Only index persons | 53.60 | 53.79 | 52.91 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2075 | 1673 | 402 |
| Unadjusted period prevalence (%) | 0.57 | 0.66 | 0.20 |
| Median age at first event (years) | 53.68 | 53.26 | 55.41 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint G6_PLANTAR and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_PLANTAR | 0.713 [0.64, 0.79] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.09 |
During the follow-up period (1.1.1998 — 31.12.2019), 656 out of 8184 females with G6_PLANTAR died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_PLANTAR | 0.803 [0.71, 0.91] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.013 |
During the follow-up period (1.1.1998 — 31.12.2019), 351 out of 2308 males with G6_PLANTAR died.
Mortality risk
Mortality risk for people of age
years, who have G6_PLANTAR.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.055% | 0.208% |
| 5 | 0.384% | 1.01% |
| 10 | 0.965% | 2.357% |
| 15 | 1.856% | 4.72% |
| 20 | 3.224% | 7.875% |
Relationships between endpoints
↥Index endpoint: G6_PLANTAR – Lesion of plantar nerve
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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