Meralgia paraesthetica

G6_MERALGIA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G57.1
  • Hospital discharge: ICD-9 3551
  • Cause of death: ICD-10 G57.1
  • Cause of death: ICD-9 3551

2 out of 7 registries used, show all original rules.

1110

4. Check minimum number of events

None

1110

5. Include endpoints

None

1110

6. Filter based on genotype QC (FinnGen only)

1068

Control definitions (FinnGen only)

Control exclude G6_NERPLEX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G57
Name in latin Meralgia paraesthetica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 7175 4161 2986
Only index persons 6822 4009 2813
Unadjusted period prevalence (%)
Whole population 0.10 0.12 0.08
Only index persons 0.13 0.15 0.11
Median age at first event (years)
Whole population 53.63 53.84 53.35
Only index persons 53.28 53.42 53.08

-FinnGen-

Key figures

All Female Male
Number of individuals 1068 640 428
Unadjusted period prevalence (%) 0.24 0.25 0.21
Median age at first event (years) 53.55 52.33 55.38

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Association

Association between endpoint G6_MERALGIA and mortality.

Females

Parameter HR [95% CI] p-value
G6_MERALGIA 0.954 [0.84, 1.09] 0.481
Birth year 0.994 [0.99, 1.0] 0.192

During the follow-up period (1.1.1998 — 31.12.2019), 356 out of 3285 females with G6_MERALGIA died.

Males

Parameter HR [95% CI] p-value
G6_MERALGIA 0.941 [0.81, 1.09] 0.428
Birth year 0.99 [0.98, 1.0] 0.027

During the follow-up period (1.1.1998 — 31.12.2019), 280 out of 2358 males with G6_MERALGIA died.

Mortality risk

Mortality risk for people of age

years, who have G6_MERALGIA.

N-year risk Females Males
1 0.106% 0.21%
5 0.667% 1.181%
10 1.499% 2.853%
15 2.717% 5.396%
20 4.711% 9.395%

Relationships between endpoints

Index endpoint: G6_MERALGIA – Meralgia paraesthetica

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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