No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
940 |
4. Check minimum number of eventsNone |
940 |
5. Include endpointsNone |
940 |
6. Filter based on genotype QC (FinnGen only) |
899 |
Control definitions (FinnGen only)
Control exclude
G6_NERPLEX
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G56
Name in latin
Alia morbositas nervi mediani
Similar endpoints
↥List of similar endpoints to
Other lesions of median nerve
based on the number of shared cases.
Similar with more cases:
- Nerve, nerve root and plexus disorders
- Neurological diseases
- Neurological diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 9440 | 6480 | 2874 |
| Only index persons | 7476 | 5256 | 2220 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.15 | 0.19 | 0.08 |
| Only index persons | 0.16 | 0.19 | 0.08 |
| Median age at first event (years) | |||
| Whole population | 50.58 | 50.84 | 49.78 |
| Only index persons | 48.51 | 49.05 | 47.24 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 899 | 605 | 294 |
| Unadjusted period prevalence (%) | 0.21 | 0.24 | 0.15 |
| Median age at first event (years) | 46.04 | 45.56 | 47.02 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint G6_MEDLEOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_MEDLEOTH | 0.892 [0.75, 1.07] | 0.212 |
| Birth year | 0.998 [0.99, 1.01] | 0.646 |
During the follow-up period (1.1.1998 — 31.12.2019), 141 out of 1512 females with G6_MEDLEOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_MEDLEOTH | 1.025 [0.82, 1.28] | 0.823 |
| Birth year | 0.984 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 169 out of 1159 males with G6_MEDLEOTH died.
Mortality risk
Mortality risk for people of age
years, who have G6_MEDLEOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.081% | 0.187% |
| 5 | 0.625% | 1.053% |
| 10 | 1.59% | 2.713% |
| 15 | 2.958% | 4.969% |
| 20 | 5.052% | 8.629% |
Relationships between endpoints
↥Index endpoint: G6_MEDLEOTH – Other lesions of median nerve
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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