femoral neuropathy: Neuropathy of the femoral nerve.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
252 |
4. Check minimum number of eventsNone |
252 |
5. Include endpointsNone |
252 |
6. Filter based on genotype QC (FinnGen only) |
246 |
Control definitions (FinnGen only)
Control exclude
G6_NERPLEX
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G57
Name in latin
Morbositas nervi femoralis
Similar endpoints
↥List of similar endpoints to
Lesion of femoral nerve
based on the number of shared cases.
Similar with more cases:
- Nerve, nerve root and plexus disorders
- Neurological diseases
- Neurological diseases
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1898 | 1197 | 693 |
| Only index persons | 1739 | 1132 | 607 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.03 | 0.02 |
| Only index persons | 0.04 | 0.04 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 52.40 | 52.31 | 52.41 |
| Only index persons | 51.40 | 51.82 | 50.61 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 246 | 180 | 66 |
| Unadjusted period prevalence (%) | 0.06 | 0.07 | 0.03 |
| Median age at first event (years) | 50.01 | 50.05 | 49.89 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint G6_FEMLE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_FEMLE | 0.953 [0.78, 1.16] | 0.637 |
| Birth year | 0.996 [0.99, 1.0] | 0.355 |
During the follow-up period (1.1.1998 — 31.12.2019), 114 out of 1038 females with G6_FEMLE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_FEMLE | 1.514 [1.24, 1.85] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 147 out of 596 males with G6_FEMLE died.
Mortality risk
Mortality risk for people of age
years, who have G6_FEMLE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.114% | 0.246% |
| 5 | 0.603% | 1.748% |
| 10 | 1.412% | 4.45% |
| 15 | 2.804% | 8.239% |
| 20 | 5.006% | 13.697% |
Relationships between endpoints
↥Index endpoint: G6_FEMLE – Lesion of femoral nerve
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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