peroneal nerve paralysis: Paralysis of the nerves located in the legs.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1668 |
4. Check minimum number of eventsNone |
1668 |
5. Include endpointsNone |
1668 |
6. Filter based on genotype QC (FinnGen only) |
1618 |
Control definitions (FinnGen only)
Control exclude
G6_NERPLEX
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G57
Name in latin
Morbositas nervi fibularis
Similar endpoints
↥List of similar endpoints to
Lesion of lateral popliteal nerve
based on the number of shared cases.
Similar with more cases:
- Nerve, nerve root and plexus disorders
- Neurological diseases
- Neurological diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 14471 | 5607 | 8795 |
| Only index persons | 13113 | 5181 | 7932 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.21 | 0.16 | 0.25 |
| Only index persons | 0.26 | 0.19 | 0.30 |
| Median age at first event (years) | |||
| Whole population | 53.69 | 55.05 | 52.80 |
| Only index persons | 52.91 | 53.93 | 52.25 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1618 | 726 | 892 |
| Unadjusted period prevalence (%) | 0.37 | 0.29 | 0.45 |
| Median age at first event (years) | 55.09 | 52.24 | 57.41 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint G6_FEMLAPOP and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_FEMLAPOP | 1.818 [1.6, 2.07] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.132 |
During the follow-up period (1.1.1998 — 31.12.2019), 953 out of 4580 females with G6_FEMLAPOP died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_FEMLAPOP | 1.867 [1.67, 2.09] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 1732 out of 7148 males with G6_FEMLAPOP died.
Mortality risk
Mortality risk for people of age
years, who have G6_FEMLAPOP.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.159% | 0.431% |
| 5 | 0.923% | 2.211% |
| 10 | 2.386% | 5.452% |
| 15 | 4.651% | 10.167% |
| 20 | 7.997% | 16.748% |
Relationships between endpoints
↥Index endpoint: G6_FEMLAPOP – Lesion of lateral popliteal nerve
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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