No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2036 |
4. Check minimum number of eventsNone |
2036 |
5. Include endpointsNone |
2036 |
6. Filter based on genotype QC (FinnGen only) |
1959 |
Control definitions (FinnGen only)
Control exclude
G6_OTHNEU
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G90-G99
Name in latin
Aliae morbositates cerebri
Similar endpoints
↥List of similar endpoints to
Cerebral cysts
based on the number of shared cases.
Similar with more cases:
- Other neurological diseases
- Neurological diseases
- Neurological diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 20739 | 9226 | 11265 |
| Only index persons | 15721 | 7529 | 8192 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.29 | 0.26 | 0.31 |
| Only index persons | 0.30 | 0.28 | 0.31 |
| Median age at first event (years) | |||
| Whole population | 52.04 | 47.69 | 55.28 |
| Only index persons | 49.56 | 44.95 | 53.80 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1959 | 1079 | 880 |
| Unadjusted period prevalence (%) | 0.43 | 0.42 | 0.44 |
| Median age at first event (years) | 49.81 | 42.14 | 59.20 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint G6_CERCYST and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_CERCYST | 3.663 [3.19, 4.21] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.072 |
During the follow-up period (1.1.1998 — 31.12.2019), 1185 out of 5799 females with G6_CERCYST died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_CERCYST | 3.775 [3.36, 4.24] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.013 |
During the follow-up period (1.1.1998 — 31.12.2019), 2063 out of 6201 males with G6_CERCYST died.
Mortality risk
Mortality risk for people of age
years, who have G6_CERCYST.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.347% | 0.85% |
| 5 | 2.303% | 4.934% |
| 10 | 5.1% | 11.518% |
| 15 | 9.267% | 21.045% |
| 20 | 15.851% | 33.472% |
Relationships between endpoints
↥Index endpoint: G6_CERCYST – Cerebral cysts
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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