Bell's palsy: Partial or complete paralysis of the facial muscles of one side of a person's face. It is caused by damage to the seventh cranial nerve. It is usually temporary but it may recur.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
4468 |
4. Check minimum number of eventsNone |
4468 |
5. Include endpointsNone |
4468 |
6. Filter based on genotype QC (FinnGen only) |
4270 |
Control definitions (FinnGen only)
Control exclude
G6_NERPLEX
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G51
Name in latin
Paresis nervi facialis
Similar endpoints
↥List of similar endpoints to
Bell's palsy
based on the number of shared cases.
Similar with more cases:
- Nerve, nerve root and plexus disorders
- Neurological diseases
- Neurological diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 41280 | 21652 | 19358 |
| Only index persons | 36873 | 19506 | 17367 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.58 | 0.62 | 0.54 |
| Only index persons | 0.69 | 0.72 | 0.66 |
| Median age at first event (years) | |||
| Whole population | 51.87 | 52.85 | 50.80 |
| Only index persons | 50.32 | 51.08 | 49.47 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 4270 | 2398 | 1872 |
| Unadjusted period prevalence (%) | 0.94 | 0.94 | 0.94 |
| Median age at first event (years) | 53.00 | 50.27 | 56.51 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint G6_BELLPA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_BELLPA | 1.24 [1.13, 1.36] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.21 |
During the follow-up period (1.1.1998 — 31.12.2019), 2774 out of 16681 females with G6_BELLPA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_BELLPA | 1.149 [1.05, 1.26] | 0.004 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 2668 out of 15120 males with G6_BELLPA died.
Mortality risk
Mortality risk for people of age
years, who have G6_BELLPA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.126% | 0.226% |
| 5 | 0.737% | 1.389% |
| 10 | 1.735% | 3.341% |
| 15 | 3.486% | 6.307% |
| 20 | 5.89% | 10.913% |
Relationships between endpoints
↥Index endpoint: G6_BELLPA – Bell's palsy
GWS hits: 4
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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