No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
449 |
4. Check minimum number of eventsNone |
449 |
5. Include endpointsNone |
449 |
6. Filter based on genotype QC (FinnGen only) |
436 |
Control definitions (FinnGen only)
Control exclude
G6_OTHNEU
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G93
Name in latin
Laesio anoxica cerebri non alibi classificata
Similar endpoints
↥List of similar endpoints to
Anoxic brain damage
based on the number of shared cases.
Similar with more cases:
- Other neurological diseases
- Neurological diseases
- Neurological diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7504 | 2213 | 5132 |
| Only index persons | 4082 | 1219 | 2863 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.12 | 0.06 | 0.14 |
| Only index persons | 0.09 | 0.04 | 0.11 |
| Median age at first event (years) | |||
| Whole population | 60.56 | 61.03 | 60.15 |
| Only index persons | 60.34 | 60.12 | 60.43 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 436 | 116 | 320 |
| Unadjusted period prevalence (%) | 0.13 | 0.05 | 0.16 |
| Median age at first event (years) | 62.99 | 58.75 | 64.53 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint G6_ANOXBRAINDAM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_ANOXBRAINDAM | 5.632 [4.28, 7.42] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.638 |
During the follow-up period (1.1.1998 — 31.12.2019), 257 out of 594 females with G6_ANOXBRAINDAM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_ANOXBRAINDAM | 4.447 [3.79, 5.22] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.062 |
During the follow-up period (1.1.1998 — 31.12.2019), 781 out of 1580 males with G6_ANOXBRAINDAM died.
Mortality risk
Mortality risk for people of age
years, who have G6_ANOXBRAINDAM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.472% | 1.023% |
| 5 | 3.401% | 5.482% |
| 10 | 9.156% | 13.608% |
| 15 | 16.581% | 24.711% |
| 20 | 27.016% | 40.035% |
Relationships between endpoints
↥Index endpoint: G6_ANOXBRAINDAM – Anoxic brain damage
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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