Physiological and behavioural disorders associated with sexual development and orientation

F5_SEXUAL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F66
  • Hospital discharge: ICD-9 3020
  • Cause of death: ICD-10 F66
  • Cause of death: ICD-9 3020

2 out of 7 registries used, show all original rules.

57

4. Check minimum number of events

None

57

5. Include endpoints

None

57

6. Filter based on genotype QC (FinnGen only)

55

Control definitions (FinnGen only)

Control exclude F5_PERSOBEH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F63-F69
Name in latin Perturbationes psychologicae et modi se gerendi ad formationem et orientationem sexualem adjunctae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 587 240 347
Only index persons 527 218 309
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population - 35.04 23.08
Only index persons 26.20 32.73 21.59

-FinnGen-

Key figures

All Female Male
Number of individuals 55 33 22
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 34.48 37.11 30.54

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

Association

Association between endpoint F5_SEXUAL and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have F5_SEXUAL.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: F5_SEXUAL – Physiological and behavioural disorders associated with sexual development and orientation

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data