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Histrionic personality disorder

DOID EFO Endpoint Browser PheWeb

F5_HISPER

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F60.4
  • Hospital discharge: ICD-9 — 3015
  • Hospital discharge: ICD-8 — 3015
  • Cause of death: ICD-10 — F60.4
  • Cause of death: ICD-9 — 3015
  • Cause of death: ICD-8 — 3015

2 out of 7 registries used, show all original rules.

166

4. Check minimum number of events

None

166

5. Include endpoints

None

166

6. Filter based on genotype QC (FinnGen only)

158

Control definitions (FinnGen only)

Control exclude F5_PERSOBEH

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F60
Name in latin Personalitas histrionica

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1630 1108 491
Only index persons 1208 870 338
Unadjusted period prevalence (%)
Whole population 0.03 0.03 0.01
Only index persons 0.03 0.03 0.01
Median age at first event (years)
Whole population 37.99 39.56 33.95
Only index persons 35.62 37.32 31.25

-FinnGen-

Key figures

All Female Male
Number of individuals 158 116 42
Unadjusted period prevalence (%) 0.04 0.05 0.02
Median age at first event (years) 31.73 30.94 33.91

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

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Association

Association between endpoint F5_HISPER and mortality.

Females

Parameter HR [95% CI] p-value
F5_HISPER 3.111 [2.32, 4.18] < 0.001
Birth year 0.994 [0.99, 1.0] 0.171

During the follow-up period (1.1.1998 — 31.12.2019), 69 out of 395 females with F5_HISPER died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have F5_HISPER.

N-year risk Females Males
1 0.352% No data
5 1.577% No data
10 4.391% No data
15 7.889% No data
20 13.936% No data

Relationships between endpoints

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Index endpoint: F5_HISPER – Histrionic personality disorder

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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