No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
589 |
4. Check minimum number of eventsNone |
589 |
5. Include endpointsNone |
589 |
6. Filter based on genotype QC (FinnGen only) |
557 |
Control definitions (FinnGen only)
Control exclude
F5_PERSOBEH
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F63-F69
Name in latin
Perturbationes habituum et impulsuum
Similar endpoints
↥List of similar endpoints to
Habit and impulse disorders
based on the number of shared cases.
Similar with more cases:
- Disorders of adult personality and behaviour
- Any mental disorder
- Psychiatric diseases
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6737 | 2297 | 4406 |
| Only index persons | 6147 | 2125 | 4022 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.07 | 0.12 |
| Only index persons | 0.13 | 0.08 | 0.15 |
| Median age at first event (years) | |||
| Whole population | 25.91 | 28.58 | 24.44 |
| Only index persons | 25.47 | 27.90 | 24.18 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 557 | 227 | 330 |
| Unadjusted period prevalence (%) | 0.13 | 0.09 | 0.17 |
| Median age at first event (years) | 34.20 | 34.61 | 33.91 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint F5_HABIT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_HABIT | 2.319 [1.81, 2.98] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.074 |
During the follow-up period (1.1.1998 — 31.12.2019), 179 out of 1743 females with F5_HABIT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_HABIT | 2.676 [2.17, 3.3] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 298 out of 2960 males with F5_HABIT died.
Mortality risk
Mortality risk for people of age
years, who have F5_HABIT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.147% | 0.549% |
| 5 | 1.025% | 3.198% |
| 10 | 2.895% | 8.048% |
| 15 | 5.603% | 15.009% |
| 20 | 10.108% | 24.073% |
Relationships between endpoints
↥Index endpoint: F5_HABIT – Habit and impulse disorders
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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