≡ Risteys
FG R11 + FR

Documentation Changelog GitHub Contact & Feedback

Dependent personality disorder

DOID EFO Endpoint Browser PheWeb

F5_DEPPER

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F60.7
  • Hospital discharge: ICD-9 — 3016
  • Hospital discharge: ICD-8 — 3016
  • Cause of death: ICD-10 — F60.7
  • Cause of death: ICD-9 — 3016
  • Cause of death: ICD-8 — 3016

2 out of 7 registries used, show all original rules.

710

4. Check minimum number of events

None

710

5. Include endpoints

None

710

6. Filter based on genotype QC (FinnGen only)

688

Control definitions (FinnGen only)

Control exclude F5_PERSOBEH

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F60
Name in latin Personalitas dependens

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5983 3858 2082
Only index persons 5050 3420 1630
Unadjusted period prevalence (%)
Whole population 0.09 0.11 0.06
Only index persons 0.11 0.13 0.06
Median age at first event (years)
Whole population 41.52 43.53 37.69
Only index persons 41.10 43.03 37.06

-FinnGen-

Key figures

All Female Male
Number of individuals 688 493 195
Unadjusted period prevalence (%) 0.17 0.19 0.10
Median age at first event (years) 41.71 41.97 41.05

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

Mortality – FinRegistry

↥

Association

Association between endpoint F5_DEPPER and mortality.

Females

Parameter HR [95% CI] p-value
F5_DEPPER 2.607 [2.27, 2.99] < 0.001
Birth year 0.996 [0.99, 1.0] 0.36

During the follow-up period (1.1.1998 — 31.12.2019), 342 out of 2422 females with F5_DEPPER died.

Males

Parameter HR [95% CI] p-value
F5_DEPPER 2.902 [2.43, 3.46] < 0.001
Birth year 0.988 [0.98, 1.0] 0.011

During the follow-up period (1.1.1998 — 31.12.2019), 189 out of 886 males with F5_DEPPER died.

Mortality risk

Mortality risk for people of age

years, who have F5_DEPPER.

N-year risk Females Males
1 0.306% 0.537%
5 1.551% 3.18%
10 3.661% 8.005%
15 7.12% 14.384%
20 12.488% 24.068%

Relationships between endpoints

↥

Index endpoint: F5_DEPPER – Dependent personality disorder

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data