No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
686 |
4. Check minimum number of eventsNone |
686 |
5. Include endpointsNone |
686 |
6. Filter based on genotype QC (FinnGen only) |
663 |
Control definitions (FinnGen only)
Control exclude
F5_PERSOBEH
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F60
Name in latin
Personalitas anxifera
Similar endpoints
↥List of similar endpoints to
Anxious personality disorder
based on the number of shared cases.
Similar with more cases:
- Specific personality disorders
- Disorders of adult personality and behaviour
- Any mental disorder
- Psychiatric diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6586 | 3244 | 3328 |
| Only index persons | 6345 | 3173 | 3172 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.09 | 0.09 | 0.09 |
| Only index persons | 0.12 | 0.12 | 0.12 |
| Median age at first event (years) | |||
| Whole population | 31.88 | 31.84 | 31.90 |
| Only index persons | 31.54 | 31.61 | 31.48 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 663 | 413 | 250 |
| Unadjusted period prevalence (%) | 0.15 | 0.16 | 0.13 |
| Median age at first event (years) | 34.68 | 34.96 | 34.23 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint F5_ANXPER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_ANXPER | 2.031 [1.64, 2.51] | < 0.001 |
| Birth year | 0.994 [0.98, 1.0] | 0.235 |
During the follow-up period (1.1.1998 — 31.12.2019), 110 out of 2540 females with F5_ANXPER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_ANXPER | 2.306 [1.95, 2.72] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.029 |
During the follow-up period (1.1.1998 — 31.12.2019), 215 out of 2580 males with F5_ANXPER died.
Mortality risk
Mortality risk for people of age
years, who have F5_ANXPER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.19% | 0.533% |
| 5 | 1.135% | 2.685% |
| 10 | 2.929% | 6.836% |
| 15 | 5.855% | 13.274% |
| 20 | 10.102% | 22.534% |
Relationships between endpoints
↥Index endpoint: F5_ANXPER – Anxious personality disorder
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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