testicular disease: A non-neoplastic or neoplastic disorder affecting the testis. Representative examples include torsion, infarction, germ cell tumor, sex cord-stromal tumor, lymphoma, and leukemia.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleonly males |
207946 |
2. Check conditionsNone |
207946 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
131 |
4. Check minimum number of eventsNone |
131 |
5. Include endpointsNone |
131 |
6. Filter based on genotype QC (FinnGen only) |
126 |
Control definitions (FinnGen only)
Extra metadata
Similar endpoints
↥List of similar endpoints to Testicular dysfunction, other/unspecified based on the number of shared cases.
Similar with more cases:
- Testicular dysfunction
- Disorders of other endocrine glands
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 1111 | - | 1111 |
Only index persons | 1058 | - | 1058 |
Unadjusted period prevalence (%) | |||
Whole population | 0.03 | - | 0.03 |
Only index persons | 0.04 | - | 0.04 |
Median age at first event (years) | |||
Whole population | - | - | 39.11 |
Only index persons | - | - | 39.11 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 126 | - | 126 |
Unadjusted period prevalence (%) | 0.06 | - | 0.06 |
Median age at first event (years) | 50.87 | - | 50.87 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint E4_TESTICDYSNAS and mortality.
Females
No dataMales
Parameter | HR [95% CI] | p-value |
---|---|---|
E4_TESTICDYSNAS | 1.564 [1.05, 2.32] | 0.026 |
Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 52 out of 694 males with E4_TESTICDYSNAS died.
Mortality risk
Mortality risk for people of age
years, who have E4_TESTICDYSNAS.N-year risk | Females | Males |
---|---|---|
1 | No data | 0.294% |
5 | No data | 1.847% |
10 | No data | 4.324% |
15 | No data | 8.11% |
20 | No data | 13.644% |
Relationships between endpoints
↥Index endpoint: E4_TESTICDYSNAS – Testicular dysfunction, other/unspecified
GWS hits: -